A New Paradigm for Severe COVID

This new model I developed explains how the depletion of arginine and tryptophan and the sequestration of cysteine leads to T cell suppression in severe COVID and may reflect the rapid onset of a somewhat cancer-reminiscent state where vitamins A and D and other myeloid differentiation factors run out.

The written version with references and links to research is available here:

https://chrismasterjohnphd.substack.com/p/a-new-paradigm-for-severe-covid

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Vitamins A and D should be properly balanced with each other, and with vitamins E and K. My COVID-specific recommendations for this balance are in the COVID Guide, and recommendations for balancing them in various different contexts are included in the Vitamins and Minerals 101 Cliff Notes, both of which are freely available to paid Substack subscribers.

These also contain general (Cliff Notes) or COVID-specific (COVID Guide) information for managing all the other nutrients mentioned. I will be updating the COVID guide next time to include tryptophan and N-acetylcysteine whenever arginine is used, but other than that this new paradigm does not alter the protocol. It does, however, move much more emphasis to A and D, and bring A onto much more equal footing with D.

I am not a medical doctor and this is not medical advice. My goal is to empower you with information. Please make all health decisions yourself, consulting sources you trust, including a caring health care professional.

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