AI Is Coming Up With Brand New Molecules, Fueling Drug Discovery

A recent study in the journal Nature unveiled new proteins that can neutralize the deadliest of snake venoms. They’re “new” in that they aren’t found in nature—they were created in a lab, dreamed up by AI.

Using AI to discover, or design, the building blocks of drugs is a fast-growing area of research. Another team of scientists out of Philadelphia is using AI to discover new antibiotics by resurrecting long-lost molecules from extinct species like neanderthals and woolly mammoths.

We know what you’re thinking: It sounds too sci-fi to be true.

Flora Lichtman talks with two pioneers in the field about how AI is supercharging drug discovery: Dr. César de la Fuente, bioengineer and presidential associate professor at the University of Pennsylvania in Philadelphia, and Nobel laureate Dr. David Baker, director of the Institute for Protein Design and professor at the University of Washington in Seattle.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

For our Los Angeles listeners: We’re working on a story about the toxins left behind by the fires and we want to hear from you. How is this affecting you? Are you worried about the air and water and soil? How are you approaching clean-up? And what questions do you have?

Leave us a voicemail at 1-646-767-6532 or send us an email at scifri@sciencefriday.com.

Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.