JAMA Editors' Summary The Microbiome and Cancer, Timing of Antihypertensive Medication Administration, What is Chronic Migraine and more
May 16, 2025
Dive into the intriguing connection between gut microbes and cancer treatment, exploring how diet and fecal transplants can boost immunotherapy. Discover the latest findings on the timing of antihypertensive medication, revealing bedtime doses don't cut cardiovascular risk as morning doses do. Learn about the troubling health impacts following the end of SNAP emergency allotments and the current state of syphilis screening in pregnancy. Unpack new insights on chronic migraine diagnosis and management for better patient outcomes.
AI Snips
Chapters
Transcript
Episode notes
Bedtime Dosing Not Superior
- The BedMed randomized trial found bedtime antihypertensive dosing was safe but did not reduce cardiovascular risk versus morning dosing.
- The trial strengthens evidence that bedtime dosing may not be superior to morning dosing.
Consider Amiloride For Resistant Hypertension
- Consider amiloride as a noninferior alternative to spironolactone for resistant hypertension based on trial results.
- Clinicians can view amiloride as an effective treatment option for lowering home systolic blood pressure.
SNAP Cutbacks Hurt Health
- Ending SNAP emergency allotments was associated with increases in poor physical health days and food insecurity.
- Policy rollbacks can have rapid measurable negative effects on population health.