The Optispan Podcast with Matt Kaeberlein

Gut Health: Science-Backed Tips For Leaky Gut, IBS, & Your Microbiome | Dr. Mary Pardee | 105

Mar 13, 2025
Dr. Mary Pardee, co-founder and CEO of DeepMind, shares her expertise on gut health and the microbiome. She delves into the complexities of IBS, discussing effective treatment options through diet and lifestyle changes. The conversation debunks myths surrounding microbiome testing and evaluates the reliability of direct-to-consumer tests. Mary emphasizes the importance of probiotics and sheds light on the supplement market, revealing what's genuinely beneficial for gut health. This insightful talk is packed with science-backed tips for long-term wellness!
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ANECDOTE

Personal Gut Health Journey

  • Dr. Mary Pardee became a doctor to fix her own chronic GI issues.\n- She uses her experience to strongly differentiate between effective treatments and snake oil.
INSIGHT

Limits of Microbiome Testing

  • Current direct-to-consumer microbiome tests lack clinical utility and precision.\n- We don't know enough to make health decisions from these tests yet.
ADVICE

Targeted Probiotic Use

  • Use probiotics selectively based on strains shown to help specific conditions.\n- Avoid broad-spectrum probiotics for healthy individuals without complaints.
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