The Metabolic Classroom with Dr. Ben Bikman

Does High Insulin Lead to More Migraines?

4 snips
Mar 19, 2021
Could high insulin levels be a hidden trigger for migraines? Delve into the intriguing relationship between insulin and migraine frequency, revealing potential links between metabolic health and headaches. Discover how insulin resistance can nearly double migraine attack risk and explore dietary strategies to combat the issue. The discussion highlights the need for better migraine management approaches tailored to individual metabolic profiles. Tune in for insights that could transform how migraine sufferers view their nutrition and lifestyle!
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INSIGHT

Migraineurs Show Insulin-Resistance Pattern

  • People who experience frequent migraines show metabolic differences consistent with insulin resistance compared to healthy controls.
  • Migraine sufferers had higher fasting insulin and much larger insulin spikes after a glucose load, indicating impaired glucose handling.
INSIGHT

OGTT Reveals Exaggerated Glucose And Insulin Peaks

  • During an oral glucose tolerance test migraine patients reached higher peak glucose and required almost double the insulin to clear it.
  • That response represents clear evidence of systemic insulin resistance in migraine sufferers.
INSIGHT

Two Mechanisms Tie Insulin To Migraines

  • Two plausible mechanisms link insulin resistance to migraines: brain glucose shortage and excess cerebral blood flow from insulin-driven vasodilation.
  • Elevated insulin may cause too much nitric-oxide–mediated vasodilation in brain vessels, flooding the brain with blood and triggering symptoms.
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