Neurology® Podcast

The Brain’s Action-Mode Network

Jan 30, 2025
Dr. Nico Dosenbach, a neurology professor at Washington University, dives into the intricacies of the brain's action mode network and its relationship with other critical networks. He discusses how resting state functional connectivity informs our understanding of neurological disorders. Dosenbach highlights the evolutionary roles of these networks, emphasizing their significance in goal-directed behavior. The conversation also touches on innovative neuromodulation techniques that may enhance motivation and cognitive function, potentially transforming treatment for patients.
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INSIGHT

Functional vs. Anatomical Network Definitions

  • Defining brain networks by function, rather than anatomy, offers advantages.
  • This "inside-out" approach lets brain data reveal its organization, avoiding preconceived notions.
INSIGHT

Action Mode Network: A New Name

  • The "action mode network" replaces the term "cingulo-opercular network," improving clarity in research.
  • This network is active during any goal-directed behavior, from abstract planning to physical movement.
INSIGHT

Parallel Brain Networks

  • The brain processes information in parallel networks for various purposes.
  • The action mode network handles goal-directed actions, while other networks, like the default mode and frontoparietal networks, manage self-reflection and abstract thought, respectively.
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