

GLPs: Myths, Microdosing, Studies and Cautions with McCall McPherson
Mar 31, 2025
34:01
Episode Highlights with McCall McPherson
- How GLPs were developed and how they became popular for weight loss
- What GLPs actually are and how they work
- The inflammatory pieces related to GLP use and her theory that they may reduce inflammation
- Inflammation is a common factor in chronic disease but tough to pinpoint and affect, though easy to test
- She measures HS-CRP on labs to check inflammation
- How she is seeing a consistent reduction in autoimmune antibodies with GLPs
- What to know about muscle loss with GLPs and how to maintain muscle mass if you take them: eat enough protein and strength-building activity
- Heart disease kills more people than all cancers combined
- A couple of important studies looking at cardiovascular death risk for diabetics on GLPs - 51% risk reduction with GLP use
- The select trial in non-diabetics found a 21% reduction in heart attack and stroke risk with GLPs
- How being undernourished and underhydrated can impact metrics like HRV and resting heart rate if people don’t drink enough water on this
- The real data about thyroid risk and why this is really important to understand
- Dosing is so important and overdosing is responsible for the majority of issues
Resources Mentioned