Huberman Lab

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

1611 snips
Dec 15, 2025
Dr. Martin Picard, a behavioral medicine professor at Columbia University, shares insights on how our behavior influences mitochondrial energy production and aging. He explains that our mindset, relationships, and lifestyle choices directly affect our vitality. Discover how practices like exercise, sleep, and meditation can recharge our energy levels. Picard also reveals that hair greying is linked to cellular stress and potentially reversible, shedding light on the connection between our psychological state and physical well-being.
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00:00 / 00:00

Energy As Flow And Potential

  • Energy is the potential for change and it flows and transforms across forms inside organisms.
  • Mitochondria pattern and translate biochemical energy into signals that shape physiology and experience.
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Mitochondria As Information Processors

  • Mitochondria act as an information‑processing system that patterns raw biochemical energy into meaningful cellular messages.
  • Different organs get mitochondria adapted to their specific energy transformations during development.
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Mitotypes And Mitochondrial Division

  • Mitochondria form distinct mitotypes and exhibit division of labor analogous to social organisms.
  • Even within a single cell mitochondria populations differ in proteome, morphology, and function.
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