The Cabral Concept 3583: Is Melatonin Dangerous for Your Heart? (TT)
Nov 27, 2025
Recent headlines warn that melatonin may be dangerous for heart health, but is the fear justified? The discussion dives into a new observational study and highlights the importance of context, dosage, and existing health issues. Past research suggests melatonin can enhance cardiovascular function and lower nighttime blood pressure. Additionally, it may improve sleep quality and offer immune and metabolic benefits. Tune in for practical dosing tips and a deeper understanding of how melatonin affects heart health.
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Observational Study Limits Causality
- A recent observational study linked long-term melatonin use with more heart failure but cannot prove cause and effect.
- Dr. Stephen Cabral explains confounding factors like existing heart disease and sleep problems likely drive the result.
Melatonin Protects Arteries
- Multiple prior studies show melatonin protects endothelial function and reduces oxidative stress.
- That protection helps arteries and may limit ischemia-reperfusion injury to the heart.
Melatonin Lowers Nighttime Blood Pressure
- Nighttime melatonin lowered systolic BP by about 4–6 mmHg and diastolic by 3–4 mmHg in trials.
- Small nocturnal BP drops can move many people back into healthier ranges.