Nutrition Facts with Dr. Greger cover image

Nutrition Facts with Dr. Greger

The Effects of Resveratrol on Our Brain and Body (Part 2)

Oct 10, 2024
Explore the intriguing effects of resveratrol on brain health, delving into the discrepancies between animal studies and human trials. Learn about the potential benefits for conditions like Alzheimer’s and inflammation, but also the safety concerns of supplementation. Uncover the myths surrounding resveratrol as a miracle supplement, and engage with the ongoing debate in the scientific community. Listeners are encouraged to share personal health stories and seek out evidence-based nutrition resources.
12:45

Podcast summary created with Snipd AI

Quick takeaways

  • Resveratrol shows potential cognitive benefits for Alzheimer's patients, but human studies reveal inconsistent results, highlighting translation challenges from animal models.
  • Research indicates resveratrol may undermine some positive exercise outcomes in older adults while raising safety concerns over gastrointestinal issues and toxicity.

Deep dives

Resveratrol and Brain Health

Resveratrol shows potential for impacting age-related cognitive decline, particularly in the context of aging and menopause. While animal studies suggest positive cognitive effects, human studies present mixed results, casting doubt on its efficacy as a cognitive enhancer for people. For instance, a study found that patients with mild to moderate Alzheimer's who received resveratrol did see some cognitive improvement, but subsequent attempts to replicate this had disappointing results, revealing no significant benefits after high doses were administered. This disparity highlights the challenges in translating animal model successes into effective human treatments, as evidenced by findings that suggest high doses might not yield the desired cognitive benefits.

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