Science Friday

Why Are There So Many Drug Shortages In The U.S.?

Jul 18, 2024
Exploring the impact of 323 active drug shortages in the U.S. healthcare system, including challenges faced by patients and doctors. Issues with antibiotic shortages, health equity impacts, and scarcity of essential medications. Pediatric oncologists frustrated with VINBLASTINE shortages for children with cancer. Solutions like manufacturing advancements and governmental interventions discussed.
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ANECDOTE

Sarah's Methotrexate Struggle

  • Sarah Louise Butler, diagnosed with rheumatoid arthritis, took methotrexate for 13 years.
  • Switching to injectable form led to shortages during the pandemic, forcing her to a costlier alternative.
INSIGHT

Generic vs. Brand Name Drug Costs

  • Methotrexate, a generic drug, is significantly cheaper than brand-name alternatives like Simzia.
  • Generics face pricing pressures, while brand-name drugs often have higher profit margins.
INSIGHT

Injectable Methotrexate Shortages

  • Injectable methotrexate, a generic sterile injectable, is prone to shortages.
  • These injectables constitute a significant portion of drug shortages, being more complex to manufacture than pills.
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