Huberman Lab Essentials: The Science of Gratitude & How to Build a Gratitude Practice
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Oct 23, 2025 Delve into the science of gratitude and its brain-boosting benefits. Discover why typical gratitude lists fall short compared to engaging storytelling practices. Learn how gratitude triggers specific brain areas, enhancing social connection and reducing anxiety. Explore the importance of authentic experiences over mere expressions of thanks. Gain insights into effective gratitude rituals that can improve mental and physical health, including a practical exercise to cultivate genuine appreciation through meaningful narratives.
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Gratitude Shifts Brain Circuits
- Gratitude is a potent pro-social mindset that shifts neural circuits toward approach and connection.
- Repeated practice can tilt brain physiology to favor pro-social over defensive responses.
Serotonin Activates Gratitude Networks
- Serotonin from raphe nuclei activates medial prefrontal and anterior cingulate cortices during gratitude.
- Those areas set context and motivate approach, increasing desire to engage with valued experiences.
Don't Fake Gratitude
- Avoid fake-it-until-you-make-it gratitude because the brain detects insincerity and won't yield benefits.
- Instead, use practices that genuinely engage prefrontal context-setting to create positive physiological effects.