Cautionary Tales with Tim Harford

How To End A Pandemic

Jul 17, 2020
Discover the gripping tale of smallpox eradication, showcasing an unlikely alliance that changed history. Delve into the ethical dilemmas faced by Cotton Mather in early inoculation efforts and the societal backlash that followed. Explore the chilling implications of Operation Dark Winter, a simulated smallpox outbreak that underscores the vital need for vaccine preparedness. Learn how the lessons from smallpox can inform our ongoing battle against modern pandemics, emphasizing innovation and vigilance in the face of infectious diseases.
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ANECDOTE

Boston Smallpox Outbreak

  • In 1721, Boston faced a smallpox outbreak, prompting Cotton Mather to advocate for inoculation based on African practices.
  • Despite resistance, Dr. Zabdiel Boylston inoculated his son and slaves, leading to a safer smallpox experience.
ANECDOTE

Boylston's Experiment

  • Dr. Boylston's inoculation of his own son, despite public outcry, demonstrated his conviction in the method's potential.
  • While his son's high fever caused concern, his eventual recovery provided early evidence of inoculation's effectiveness.
ANECDOTE

Bombing of Mather's House

  • Despite growing acceptance of inoculation, resistance remained, exemplified by the bombing of Cotton Mather's house.
  • The bomb, intended to harm Mather and his nephew, failed to detonate, underscoring the volatile atmosphere surrounding inoculation.
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