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In this episode, I tackle one of the most persistent myths in the testosterone world. We are talking about estrogen – and why it is not the enemy for men on testosterone therapy.
I was inspired to record this after hearing that the FDA removed the black box warning from estrogen therapy for women. That got me thinking about how, in the men’s world, estrogen has been turned into this evil hormone that must be crushed at all costs. For a lot of guys, the moment they get prescribed testosterone, they’re automatically handed an aromatase inhibitor with zero thought or nuance. I think that’s a huge mistake.
In this conversation, I walk through why routine estrogen suppression is almost never necessary for the average man on TRT and how that “block estrogen at all costs” mindset came straight out of bodybuilding folklore and bro science. I break down the clinical data showing that low estrogen in men leads to more body fat, worse bone density, lower libido, more mood issues, and worse cardiovascular health – the exact problems TRT is supposed to fix.
We get into how estradiol supports bone mineral density, fat metabolism, sexual function, brain health, and endothelial function. I also share some of my own labs and experience, plus why chasing “perfect” lab ranges while ignoring symptoms leads so many men into trouble. High-normal estrogen alongside high-normal testosterone is not only normal, it is often protective.
Finally, I lay out a better framework: fix insulin resistance, improve lifestyle, let the body aromatize naturally, and reserve aromatase inhibitors as a true last resort. If you’re on TRT, thinking about starting, or have been scared into believing estrogen is out to ruin your life, this episode will give you a completely different lens to see your hormones through.
The Hunter Williams Podcast