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JAMA Clinical Reviews

Prevention and Treatment of Severe Food Allergies

Feb 13, 2024
Doctors Onyinye I. Iweala and Yamini V. Virkud discuss severe food allergies, highlighting prevention, symptoms, and management. They explore the role of early oral exposure, benefits of children playing with food, and the top nine food allergies. The challenges faced by patients with alpha-gal syndrome, a red meat allergy caused by tick bites, are also addressed. The podcast emphasizes the importance of carrying epinephrine autoinjectors and knowing when to call 911 for severe anaphylactic reactions.
17:33

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Quick takeaways

  • Early oral exposure to foods can help prevent sensitization and the development of severe food allergies.
  • Alpha-gal syndrome, a newly recognized allergy to red meat, is associated with tick exposure and can cause delayed allergic reactions.

Deep dives

Understanding Severe Food Allergies

Severe food allergies are adverse reactions that are driven by the immune system and specifically by IgE allergy antibodies. These reactions can be potentially fatal, but actual fatalities are rare. Symptoms of severe food allergies include difficulty breathing, throat tightening, dizziness, nausea, vomiting, and severe abdominal cramping.

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