Two Onc Docs Hemoglobin Electrophoresis
Nov 11, 2024
Dive into the fascinating world of hemoglobin electrophoresis, where various types of hemoglobin are separated with electric currents. Explore the nuances of disorders like thalassemia and sickle cell disease, including their diagnostic implications. Discover how alpha thalassemias affect test results and the challenges they pose for newborns. Learn about unique variants such as hemoglobin E and Lepore, and gain valuable study tips for hematology exams. It's a must-listen for anyone interested in understanding the complexities of hemoglobinopathies!
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Board Review Resource
- Hemoglobin electrophoresis is a challenging topic.
- Utilize Dr. Alice Ma's free ASH board review lecture for effective studying.
Hemoglobin Electrophoresis Process
- Hemoglobin electrophoresis uses electric current in alkaline or acidic mediums on blood samples. Different hemoglobins have different charges, resulting in varied speeds and discrete bands.
Normal Hemoglobin Breakdown
- Normal adult hemoglobin breakdown: HbA (95-98%), HbA2 (2-3%), HbF (<1-2%).
- HbE, HbS, and HbC should be absent.