Rena Malik, MD Podcast: Optimizing Health, Sex & Relationships with Science Backed Tips from Leading Experts Moment: Why Every Man Over 40 Should Track Testosterone and Sexual Health ft. Dr. Mohit Khera
Aug 20, 2025
In this engaging discussion, Dr. Mohit Khera, a urologist specializing in men's health, emphasizes the importance of testosterone screening for men over 40. He debunks myths surrounding testosterone therapy, including its relation to prostate cancer. The conversation highlights how testosterone levels impact both physical and mental health, including depression and erectile dysfunction. Dr. Khera advocates for lifestyle changes alongside medical interventions, using semen analysis as a crucial health barometer.
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Testosterone Doesn’t Raise Prostate Or Urinary Risk
- Testosterone therapy does not increase prostate cancer risk according to AUA guidelines and recent trials.
- Studies show no worsening of urinary symptoms and some suggest long-term improvement.
Check Testosterone When Men Have Depression
- Check testosterone in men presenting with depression, PTSD, or low energy because low T commonly coexists with depressive symptoms.
- Treating low testosterone often reduces depressive symptoms and can augment antidepressants.
Shared Symptoms Require Broad Screening
- Depression and hypogonadism share many identical symptoms, so screening both is essential when symptoms persist after treatment.
- Also check other hormones like thyroid to rule out mimickers of low energy and libido.