Dr. Rosalind Watts, clinical psychologist at the Psychedelic Research Group at Imperial College London, discusses the history and resurgence of psilocybin research, embracing difficult emotions and surrendering in psychedelic experiences, the effects of psilocybin on depression, the role of psilocybin in therapy, accessing altered states beyond psychedelics, and maintaining change and connecting to self and others.
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Quick takeaways
Psilocybin deactivates the part of the brain responsible for rumination and negative thinking, showing potential for treating individuals with treatment-resistant depression.
Psychedelic research faced a decline in the past but has resurged in the early 2000s, leading to studies on the effects of psilocybin.
A clinical study conducted on 20 individuals with treatment-resistant depression showed significant improvements in depressive symptoms, although effects faded after three months.
Deep dives
The Focus of the Psychedelic Research Group
The podcast episode features Dr. Rosalind Watts, a clinical psychologist at the psychedelic research group at Imperial College of London. The group focuses on studying the action of psychedelic drugs in the brain and their clinical utility.
The Study of Psilocybin and Depression
The podcast discusses a specific research project that focuses on the effects of psilocybin (mushrooms) on depression. Psilocybin was found to deactivate the part of the brain responsible for rumination and negative thinking, making it potentially useful for individuals with treatment-resistant depression.
Background on Psychedelic Research
The podcast mentions the long history of psychedelic research, which was more prevalent in the 50s, 60s, and 70s before the substances became illegal. However, interest in psychedelics resurged in the early 2000s. The research team faced challenges with obtaining licenses and the sourcing of high-quality psilocybin for their studies.
The Psilocybin Study on Depression
The podcast describes a clinical study on 20 individuals with treatment-resistant depression. The study was the first of its kind in the UK and aimed to investigate the effects of psilocybin on depression. Participants experienced significant improvements in their depressive symptoms, although the effects seemed to diminish after three months.
Challenges and Future Directions
The podcast highlights the challenges of accessing more sessions and maintaining the positive effects of psilocybin therapy. However, it suggests that other alternative practices such as meditation and breathwork may offer similar states of consciousness and psychological benefits.
The Psychedelic Research Group focuses on two main areas: first, the action of psychedelic drugs in the brain and second, their clinical utility, e.g. as aides to psychotherapy, with a particular focus on depression.