The Gist Trump’s Mortgage Attacks and Kessler on Weight Loss
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Aug 27, 2025 
David Kessler, the former head of the FDA and author of "Diet, Drugs, and Dopamine," dives into how GLP-1 drugs are revolutionizing weight management. He discusses the failures of traditional diets and the need for a comprehensive approach to health that considers psychological factors. Kessler also reflects on the COVID-19 pandemic's impact on health and underscores the connection between obesity and chronic diseases. In a political twist, there's a heated discussion about Trump's controversial mortgage fraud claims and their implications.
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Mortgages As A Political Weapon
- Mike Pesca highlights Trump weaponizing mortgage lies as a political tactic against opponents.
- This pattern contrasts with allies who escape scrutiny, showing selective enforcement of scandal narratives.
Kessler's Personal Weight Journey
- David Kessler recounts his own repeated weight-loss attempts and limits of nutrition therapy alone.
- He explains GLP-1s calmed appetite circuits that nutrition-only approaches could not.
Use GLP-1s As A Temporary Tool
- Use GLP-1 drugs as a tool to change eating behavior rather than a standalone cure.
- Combine short-term pharmacologic help with relearning how to eat to try to sustain results.
