The Curbsiders Internal Medicine Podcast

#326 Cardiorenal Syndrome, Biomarkers, Diuretic Resistance (NephMadness 2022)

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Mar 14, 2022
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ADVICE

Managing Elevated Creatinine in ADHF

  • Don't stop a patient's ARBs or SGLT2s solely due to elevated creatinine in acute decompensated heart failure.
  • Address volume overload as the primary concern, even if creatinine rises.
INSIGHT

Venous Congestion in Cardiorenal Syndrome

  • Increased venous pressure, not decreased cardiac index, is the primary driver of worsening kidney function in cardiorenal syndrome.
  • This venous congestion slows down perfusion, leading to acute kidney injury.
ADVICE

Restarting Medications Post-ADHF

  • Restart ARBs and SGLT2 inhibitors in ADHF patients before discharge if they were stopped during admission.
  • Rapidly restarting these medications can prevent future heart failure exacerbations.
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