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Exercise plays a crucial role in preventing chronic illnesses and improving overall health. Inactivity, also known as sedentary syndrome or couch sitting, is identified as the primary cause of over 35 chronic illnesses. These include conditions like sarcopenia, metabolic syndrome, obesity, insulin resistance, diabetes, cancer, stroke, dementia, mood disorders, bone disorders, digestive issues, and even erectile dysfunction. Regular exercise enhances the immune system, reduces the risk of respiratory infections, heart disease, arrhythmias, coronary artery dysfunction, and bone disorders. Exercise also promotes the growth and strength of mitochondria, which are essential for energy production and are associated with various diseases, including cancer. Furthermore, exercise strengthens the immune system, aiding in the prevention of infections and the fight against cancer.