
Depresh Mode with John Moe Generative AI Chatbot Delivers Great Results for Mental Health. Is “Therabot” the Future?
Apr 28, 2025
Dr. Nicholas Jacobson, an associate professor at Dartmouth and director of the AIM-HI lab, explores the groundbreaking Therabot—a generative AI psychotherapy chatbot. He reveals surprising results from clinical trials, including a 51% reduction in depression symptoms among users. Jacobson discusses how users form emotional bonds with Therabot and its unique ability to personalize therapy. He addresses concerns about AI in mental health, emphasizing that while Therabot won’t replace human therapists, it serves as a valuable supplement to care.
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Generative AI Can Deliver Measurable Clinical Gains
- Dartmouth's Therabot reduced depression symptoms by 51% and anxiety by 31% in a clinical trial.
- The system delivers evidence-based psychotherapy via generative AI tailored to users' needs.
Treating Comorbidity With Contextual Responses
- Therabot uses generative AI to integrate comorbid issues rather than separate modular modules.
- That allows personalized, contextualized responses similar to how human therapists link interconnected problems.
Curated Data Beats Raw Internet For Therapy
- Therabot's quality depends on curated, evidence-based training data rather than the open internet.
- Dartmouth created dialogues and expert-reviewed vignettes to teach the model proven therapeutic techniques.
