The Truth About Tylenol And NSAIDs | Solo

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Sep 26, 2025

Dive into a revealing discussion about the risks of Tylenol and NSAIDs, as long-term use can lead to gut damage and emotional blunting. Explore the controversial links between acetaminophen and neurodevelopmental disorders, and learn about hidden overdose risks, especially when mixed with alcohol. Historical insights on pain medications and alarming statistics from the Vioxx scandal shed light on current prescribing practices. Dr. Tyna also highlights safer, alternative pain relief methods and emphasizes a holistic approach to managing pain.

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ADVICE

Use Minimal Effective Dosing

If you rely on OTC pain meds regularly, consult a clinician to lower dose or manage alternatives.
Use the minimal effective dose and avoid repeating doses unnecessarily.

ANECDOTE

Using Medication Response To Diagnose

Tyna asks patients what med helps and uses their response to infer pain drivers like inflammation.
She reports ibuprofen often identifies inflammatory pain while Tylenol rarely helps.

INSIGHT

Prenatal Acetaminophen Risk Signal

Multiple studies link prenatal acetaminophen to higher ADHD and ASD risk in offspring.
A Navigation Guide meta-analysis concluded evidence supports limiting acetaminophen in pregnancy.

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EP. 232: Grab my FREE 4 Part Video Series: GLP1s Uncovered: https://bit.ly/GLP1uncovered

In this episode I’m clearing up the confusion and political noise around Tylenol and NSAIDs. These over the counter medications are handed out like candy, yet decades in practice treating pain have shown me how often they backfire: from gut damage and hormone disruption to stalled healing and liver stress. Add in the recent headlines about Tylenol’s potential link to autism, and suddenly what was once considered safe has become a lightning rod of controversy.

I’ll break it down simply: what these meds really do in the body, why long-term reliance can set you up for bigger problems, and how to think critically instead of getting caught in the political crossfire. This is not about fear. It is about facts, context, and giving you tools to make better choices for your health. Plus I let you know what to you can do instead.

Topics Discussed:→ Is Tylenol safe for long-term use?→ What are the risks of ibuprofen and other NSAIDs?→ How does Tylenol affect liver and gut health?→ What are safer alternatives for pain relief?→ Why was the Vioxx scandal important for pain management?

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On This Episode We Cover:

→ 00:00:00 - Introduction

→ 00:04:44 - Medscape findings and Tylenol

→ 00:08:16 - Tylenol and neurodevelopment concerns

→ 00:13:51 - Common sources of acetaminophen

→ 00:16:31 - Risks of NSAIDs

→ 00:19:15 - A brief history of pain relief

→ 00:23:05 - The Vioxx scandal explained

→ 00:29:12 - Safe NSAID dosing

→ 00:33:15 - Tylenol PM and its issues

→ 00:34:12 - Black box warnings

→ 00:36:54 - Bone health risks and more

→ 00:39:16 - Gut and pregnancy safety

→ 00:42:46 - COX pathways and cartilage effects

→ 00:45:25 - Approaches to pain management

→ 00:50:02 - Hormones, HRT, and pain relief

→ 00:53:41 - Liver health considerations

→ 00:57:04 - Peptides and microdosing

→ 01:03:26 - Reliable herbal options

Show Links:

→ Acetaminophen Use During Pregnancy, Behavioral Problems, And Hyperkinetic Disorders

→ Evaluation Of The Evidence On Acetaminophen Use And Neurodevelopmental Disorders Using The Navigation Guide Methodology

Further Listening:

→ EP: 227 | How I Broke Free From The Pain Trap | Solo

→ EP. 221 | The GLP-1 Microdosing Lie: It's NOT a Weight Loss Strategy | Solo

→ EP. 196 | The Answer Is The Gym | Quick + Dirty

→ EP. 82: Movement Overrides Pain - Solo Episode

→ EP. 22: Solo Episode: The Not So Easy Answer to Pain Management

→ Playlists (Orthopedics, Hormones, Strength Training + More)

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.