Neurology® Podcast

Distinguishing Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer Disease

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Dec 5, 2024
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INSIGHT

DLB Misdiagnosis

  • Dementia with Lewy bodies (DLB) is often misdiagnosed as Alzheimer's disease.
  • Accurate and early diagnosis is crucial for proper disease management and patient care.
INSIGHT

Early DLB Symptoms

  • Core clinical DLB features (Parkinsonism, hallucinations, cognitive fluctuations, RBD) often appear two years before diagnosis.
  • Neuropsychological assessments can help differentiate MCI with Lewy bodies from MCI due to Alzheimer's.
INSIGHT

Sleep and DLB

  • Sleep disturbances like early waking or excessive naps are more common in DLB than Alzheimer's.
  • RBD is the strongest predictor of DLB, even more so than other common symptoms.
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