

Distinguishing Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer Disease
6 snips Dec 5, 2024
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DLB Misdiagnosis
- Dementia with Lewy bodies (DLB) is often misdiagnosed as Alzheimer's disease.
- Accurate and early diagnosis is crucial for proper disease management and patient care.
Early DLB Symptoms
- Core clinical DLB features (Parkinsonism, hallucinations, cognitive fluctuations, RBD) often appear two years before diagnosis.
- Neuropsychological assessments can help differentiate MCI with Lewy bodies from MCI due to Alzheimer's.
Sleep and DLB
- Sleep disturbances like early waking or excessive naps are more common in DLB than Alzheimer's.
- RBD is the strongest predictor of DLB, even more so than other common symptoms.