The Melanie Avalon Biohacking Podcast #188 - Dr. Marc Milstein: The Age-Proof Brain, Amyloid Plaques & Brain Trash, The Glymphatic System, Dementia & Alzheimer's Disease, APOE Gene Risk Factor, Memory Building, Diet For Brain Health, And More!
GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/ageproofbrain
2:35 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome!
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11:30 - Marc's Background
13:30 - Insulin Degrading Enzyme
14:50 - The Relationship Between Insulin Levels And Brain Health
16:05 - The Problem With 2 New Alzheimer's Medications
18:30 - Defining The Brain Plaques And The Relation To Cognitive Decline
20:30 - Can You Have Cognitive Decline Without Brain Waste?
21:40 - Diagnosing Brain Waste
22:40 - How To Get Rid Of Brian Waste
26:10 - The Glymphatic System
28:00 - How Is The Waste Removed
29:00 - What Is The Role Of Brain Fluid?
30:10 - Is There A Relation To Intelligence?
31:15 - The Size Of Our Brain And How It Changes
34:45 - What Is Active Learning?
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42:00 - Is Pruning More Genetic Or Environmental
43:25 - How Much Influence Do Parental Rearing Have On Brain Development?
47:30 - How We Crystalize Memories By Revisiting Them
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51:00 - Why Is APOE Connected To Cognitive Decline?
52:50 - Why Did APOE Develop?
53:40 - APOE Risk Factors
55:15 - Memory Formation
58:55 - Short Term Memory
59:30 - Working Memory
1:01:00 - Can We Lose Memories?
1:02:40 - Is Scent The Strongest Recall Of Memory?
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1:07:45 - Distractions And Focus Shift
1:10:15 - The Connection Between Vision Loss Or Hearing Loss And Dementia
1:12:05 - What About Being Born Blind Or Deaf
1:12:50 - Ways To Learn And Ways To Innovate
1:16:45 - The Diet For Brain Health