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The Readout Loud

335: A deep dive on Makary, Vertex's pain data, & 2025 predictions

Dec 19, 2024
Lizzy Lawrence, STAT's FDA reporter and expert on key FDA developments, joins the conversation to discuss her profile of Marty Makary, challenging traditional views in medicine. They delve into Vertex's recent pain drug trial results and the hurdles of breaking into the competitive pain management market. The discussion pivots to bold predictions for 2025, highlighting upcoming medication launches and the shifting dynamics within the biotech industry, particularly in gene therapy and obesity treatments.
33:43

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Marty Makary's FDA nomination has stirred optimism and skepticism, raising concerns about his ability to balance scientific advocacy within a politically charged environment.
  • The 2025 biotech landscape is expected to face challenges, with startups focusing on targeted innovations amid economic pressures and increasing competition from global markets.

Deep dives

Predictions for 2025 in Biotech

The discussion forecasts a challenging environment for the biotech sector in 2025, underscored by potential leaner operations among smaller companies. An expectation exists that significant financing rounds will become less common, with startups focusing on clinically targeted innovations instead. This trend is driven partly by economic factors and increasing competition from international markets, particularly products coming out of China. The sentiment surrounding the biotech workforce also reflects concerns over persistent layoffs and how that might impact long-term research and development efforts.

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