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335: A deep dive on Makary, Vertex's pain data, & 2025 predictions

The Readout Loud

CHAPTER

Vertex's Pain Drug Trials and Challenges

This chapter explores Vertex's development of a non-opioid pain drug for acute pain and its recent disappointing trial results in chronic pain, particularly sciatica. It examines the hurdles the company faces in transitioning from rare diseases to a competitive pain management market while emphasizing the importance of reliable data in future studies.

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