This episode begins our series on "What you may have missed at ATS 2025."

We produce over 450 million tons of plastics each year, the vast majority of which has accumulated in the environment. Increasing evidence suggests that microplastics can accumulate in a number of different organs such as the brain, but what of the lungs?

In this episode, Adam Soloff, PhD (self-described "Lorax of the Thorax"), associate professor, UPMC Hillman Cancer Center, walks us through his research to find out what these ever-present microplastics do to the lungs and the pulmonary immune system in particular. Spoiler alert: once inhaled, microplastics pass through the lung seeding many tissues of the body including the heart, brain, gut, liver, and spleen. "We found it everywhere we looked," said Dr. Soloff whose team's work begins to shed light on how microplastics damage lung immunity and may predispose us to lung disease in the future.

4:16 What is a microplastic?

6:19 Where is the most established evidence of how microplastics affects our health?

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