The Kevin Rose Show

Colleen Cutcliffe, Ph.D, Co-founder and CEO of Pendulum, My Crazy Probiotic Experiment (#40)

Jun 30, 2020
Colleen Cutcliffe, Ph.D., is the Co-founder and CEO of Pendulum, specializing in groundbreaking probiotic strains. In this engaging dialogue, she shares insights from recent studies showing how Pendulum’s probiotics can significantly lower A1C and blood sugar spikes, particularly for individuals with type 2 diabetes. Colleen discusses the novel roles of butyrate in gut health and energy metabolism, as well as the challenges of creating a biotech startup. The conversation emphasizes the importance of personalized health solutions and innovative research opportunities.
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ANECDOTE

Kevin's Pre-Diabetes

  • Kevin Rose's blood work revealed he was borderline pre-diabetic, with high glucose spikes after meals.
  • Despite monitoring and dietary changes, his glucose disposal remained inefficient.
ANECDOTE

Probiotic Impact

  • After four weeks on Pendulum, Kevin's glucose levels noticeably improved, even with occasional treats.
  • His CGM showed minimal spikes after lasagna and beer, prompting disbelief and recalibration.
ANECDOTE

Colleen's Microbiome Journey

  • Colleen Cutcliffe's interest in the microbiome stemmed from her scientific background and work at Pacific Biosciences.
  • Along with a biostatistician and physicist, they saw DNA sequencing as key to unlocking microbiome potential.
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