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All cells in the body, not just neurons, have the ability to generate electrical potentials. These electrical states are important for cell communication and can influence cell behavior. Researchers have found that electrical networks in the body are involved in controlling behavior and can also play a role in development and regeneration. By understanding and manipulating these bioelectric states, scientists hope to achieve regenerative medicine outcomes, such as limb regeneration and tissue repair. These electrical networks can also be used to trigger specific developmental processes, like eye formation, by introducing specific electrical patterns in cells. This research challenges the idea that genetic instructions alone determine anatomical outcomes and highlights the importance of physiological processes in shaping development.
Bioelectric signals have been found to play a significant role in cancer development. Electrical uncoupling of cells from their neighbors can lead to a defect in multi-cellular cooperation and the formation of tumors. By disrupting the electrical communication between cells, researchers have been able to induce cancer-like behaviors in normal cells, highlighting the physiological nature of these processes. On the other hand, by manipulating bioelectric communication, it is possible to prevent tumor formation even in the presence of cancer-causing genes. These findings suggest that bioelectric signals can override genetic defects and influence cellular behavior, providing new avenues for cancer research and potential therapeutic strategies.
Research on Xenobots, which are small organisms constructed from frog skin cells or manipulated embryos, has showcased the remarkable plasticity of cellular collectives. These cells, when released from their normal developmental constraints, have demonstrated the ability to self-organize and form new functional structures. Xenobots can exhibit locomotion and even regenerative capabilities without genetic modifications. This highlights the collective intelligence and decision-making abilities of cell groups, which can navigate morphospace and achieve complex anatomical homeostasis. This research challenges traditional notions of machine versus organism and emphasizes the need for a new vocabulary to describe and understand these dynamic biological systems.
The relationship between perception and morphogenetic coding is a fascinating area of exploration. Collective cellular behaviors and decision-making in development involve the perception of anatomical features and the ability to navigate morphospace effectively. The cells in a collective intelligence must be able to recognize patterns, perceive their position in anatomical space, and make decisions accordingly. This cellular perception and decision-making process is analogous to visual perception in neural networks. Understanding these perception-based processes can shed light on how cellular collectives build and organize structures in a coordinated manner.
The discussion explores the connection between bi electrics and regenerative capacity, suggesting that aging could be resolved by enhancing the body's ability to regenerate cells that age. The hypothesis is based on the observation that in species like planaria, which exhibit high regenerative capacity, aging is absent. However, the specifics of how factors like telomere length and the morphogenetic code relate to aging are still unknown.
The conversation acknowledges that thoughts can influence the physiological functioning of the body, referencing examples like increasing heart rate or controlling stress responses through mental practices. The idea is that thoughts and mental states can communicate with and exert influence on other cells within the body beyond conventional muscle and gland actions. While concrete examples and empirical evidence are lacking, it is seen as plausible and an area worthy of further exploration.
The discussion briefly touches on the potential overlap between bi electrics and quantum biology, particularly regarding the influence of electromagnetic fields on living cells. However, no concrete conclusions are drawn. Regarding the placebo effect, it is highlighted that there is a notable communication across levels within the body, suggesting that the mind's mental states can have an impact on physiological processes. Further research is needed to better understand and leverage this communication.
The dialogue highlights the interrelated nature of developmental biology and consciousness. It is noted that both involve information processing in goal-directed, hierarchical systems. The ability to understand and control growth, form, and cognition in biology can create insights into consciousness, and vice versa. The analogy is made between the self-organization of cells to create complex organisms and the self-organization of cognitive systems to yield consciousness.
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TIMESTAMPS:
00:00:00 Introduction
00:03:35 An overview of Michael's results of code that isn't genomic
00:07:08 What's the standard view in development biology? (compare and contrast)
00:08:30 Regenerating limbs on animals which don't have regenerative properties (watch this first)
00:17:01 Why did it take so long to discover this momentous result?
00:20:42 Precisely what is voltage and what's being visualized?
00:23:23 DNA encodes hardware, and Michael discovered the software
00:27:22 Taking a cancerous cell and making it non-cancerous, and vice versa
00:32:23 What is the Self? (on identity and ego)
00:33:55 Living robots (xenobots)
00:44:50 The terms "alive" and "dead" are almost useless now
00:47:15 Perception and the morphogenetic code
00:51:06 Immortality is possible in flatworms... What about humans?
00:52:18 Jungian archetypes and their relation to the morphogenetic code
00:54:38 Curt believes this is Nobel prize winning work
00:55:53 [Rupert Sheldrake] Morphogenetic fields vs code
00:57:05 Engineering xenobots to clean up the environment
00:58:17 5G and its possible effects?
01:00:32 Microbiome and the non-neural electric imprints
01:02:34 How do you decode the code? What factors go are in play?
01:05:57 Psychedelics ⇒ change in morphogenetics?
01:07:13 The least action principle, intelligence, and the "intention" of particles
01:16:18 Studying consciousness is a first person activity, not a third person
01:18:13 [Faraz Honarvar] Does the code differ between people?
01:19:48 Morphoceuticals
01:22:03 [Nadia Markova] How does the ML algorithm work, specifically?
01:23:46 [Sam Thompson] Biological self-emergence is "proto-algorithmic"?
01:28:36 [Thane] Should we regenerate? Isn't it beneficial to NOT regenerate?
01:31:23 [Tom] Penrose's and Hameroff's Orch OR
01:35:59 [Mo Flow] Biological clock, aging, and David Sinclair
01:38:29 [Nate Grundmann] Placebo, healing yourself with your mind, and Joe Dispenza
01:44:53 Future projects of Prof. Michael Levin
01:46:01 Consciousness and developmental biology are related
* * *
Just wrapped (April 2021) a documentary called Better Left Unsaid http://betterleftunsaidfilm.com on the topic of "when does the left go too far?" Visit that site if you'd like to watch it.
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