
 Huberman Lab
 Huberman Lab Understanding & Controlling Aggression
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 May 9, 2022  Delve into the fascinating neural mechanisms that trigger aggression and how hormones like estrogen and testosterone play crucial roles. Discover how factors such as sunlight exposure, stress levels, and competition can influence aggressive behavior. The impact of substances like caffeine and alcohol on impulsivity is also explored, alongside nutritional strategies for mood regulation. Uncover the complexities of aggression from both biological and psychological perspectives, with insights on helpful supplementation for emotional balance. 
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Hydraulic Pressure Model
- Conrad Lorenz's study of aggression introduced the "hydraulic pressure model."
- This model suggests that various factors contribute to a buildup of pressure that can lead to aggressive outbursts.
VMH's Role in Aggression
- Walter Hess's experiments on cats revealed the ventromedial hypothalamus (VMH) is crucial for aggression.
- Stimulating the VMH triggered rage; stopping stimulation calmed the cats instantly.
Estrogen Receptor Neurons & Aggression
- Estrogen receptor neurons within the VMH drive aggressive behaviors.
- Activating these neurons in male mice caused them to attack even potential mates.


