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Neurology Exam Prep Podcast

Episode 44 - Rapidly Progressive Dementia

Apr 20, 2022
Exploring the differential considerations and neurodegenerative aspects of rapidly progressive dementia, identifying key neurobehavioral symptoms, understanding varied etiologies, diverse symptom presentations, and in-depth look into Creutzfeldt-Jakob Disease variants and pathophysiology.
48:20

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Quick takeaways

  • Different neurologic diagnoses present with various cognitive patterns like memory changes, personality alterations, and cortical signs.
  • Diagnostic workup for rapidly progressive dementia includes screenings for delirium, inflammatory causes, infectious tests, and autoimmune encephalitis panels.

Deep dives

Rapidly Progressive Dementia: Key Clinical Features and Assessment

When approaching patients with rapidly progressive dementia, a crucial aspect is to focus on the timing and onset of symptoms. It is essential to ask specific questions about changes in cognitive or behavioral functions over days, weeks, or months. Patients displaying abrupt cognitive changes often have family members concerned about a rapid progression. Different neurologic diagnoses can manifest with various cognitive patterns like memory changes, personality alterations, and cortical signs.

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