The Hunter Williams Podcast Microdosing Retatrutide vs Weekly Shots
Oct 24, 2025
Explore the intriguing world of microdosing Retatrutide versus traditional weekly shots. The discussion dives into how microdosing can lead to fewer side effects and stabilize appetite and energy levels. Learn about the science behind Retatrutide, including its action on key receptors for metabolism. Discover why personalization in dosing matters and how gradual adjustments can enhance tolerability. With insights into the pros and cons of both methods, listeners gain practical recommendations for optimizing their approach.
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How Retatrutide Works
- Retatrutide is a triple agonist targeting GLP-1, GIP, and glucagon to reduce appetite, improve insulin signaling, and raise metabolic rate.
- That multi-pronged action explains its strong fat loss and relative muscle preservation compared to other GLP-1s.
Time Doses To Your Training
- If weekly dosing causes a feast–famine appetite rollercoaster that conflicts with training or recovery, consider other schedules.
- Time injections to match days when you can tolerate stronger appetite suppression or choose split dosing for training needs.
Why It’s Engineered Weekly
- Retatrutide's fatty-acid modification binds albumin and extends half-life to ~6–8 days, producing week-long receptor stimulation from one dose.
- That pharmacokinetic design prioritizes convenience and adherence for typical patients.