The Ultimate Human with Gary Brecka

24. COMT Gene Mutation: How to Supplement For Better Sleep and Reduced Anxiety | Ultimate Human Short with Gary Brecka

49 snips
Jan 4, 2024
Learn about the COMT gene mutation and its impact on the body, including neurotransmitter effects and estrogen metabolism. Discover personal struggles with sleep and overthinking. Explore the traits associated with the mutation, such as successful entrepreneurship and reliability. Understand the link between estrogen dominance and water retention. Dive into the effects of green tea and quercetin on sleep and anxiety. Find out about supplement options like methyl folate and Sam E.
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INSIGHT

COMT Mutation and Neurotransmitters

  • COMT gene downregulates fight-or-flight neurotransmitters called catecholamines.
  • Mutation causes excess catecholamines, leading to anxiety, waking mind, and obsessive behaviors.
ANECDOTE

Sage's Racing Mind at Night

  • Sage experienced racing thoughts and show tunes playing in her head at bedtime despite exhaustion.
  • This symptom was later linked to the COMT gene mutation causing an awakened mind state.
ANECDOTE

Sage’s Perfectionism Example

  • Sage described being a perfectionist who needs cleanliness and organization.
  • This reflects her compulsive tendencies linked to COMT mutation, affecting mental organization.
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