In this episode of the podcast, Dr. Max Hockstein, an Emergency Physician and Intensivist, delves into the intricacies of End-Tidal Capnography. The discussion covers the terminology surrounding this topic, its significance in understanding Minute Ventilation and Cardiac Output, and the concept of VQ matching in the lungs. Dr. Hockstein explains the working principles of modern End-Tidal measurement, including Non-Dispersive Infrared Absorption, and distinguishes between sidestream and mainstream Capnometry. The episode explores the phases of a Time Capnogram and the utility of End-Tidal in various medical scenarios, from intubation confirmation to resuscitation and preload responsiveness. The episode offers valuable insights into this critical aspect of medical monitoring and leaves listeners eagerly anticipating act two.