• The factors that affect thyroid hormone production, conversion, transport, and uptake

• How high TSH levels cause damage to the thyroid gland

• High-carb diets vs. low-carb diets for thyroid health

• Why restricting calories is not the way to go if you’re struggling with hypothyroidism

• The effects of PUFA and endotoxin on thyroid hormone activity

• The problems with both deficiencies and excesses of iron, iodine, and vitamin A for thyroid health

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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-96-avoid-low-carb-diets-fasting-and-caloric-restriction-if-you-have-hypothyroidism-hypothyroidism-part-2/

Timestamps:

0:00 – intro 

1:28 – the factors that affect thyroid hormone production, conversion, transport, and uptake

3:45 – the impact of stress on thyroid hormone production and conversion 

5:02 – how the stress hormones and inflammatory cytokines affect thyroid hormone production and conversion

16:44 – thyroid hormones increase sensitivity to stress hormones 

21:44 – elevated free fatty acids, especially PUFA, inhibit thyroid hormone binding

23:26 – how a lack of energy prevents the cells from taking up thyroid hormone

30:00 – how oxidative stress affects thyroid hormone production and the effects of TSH on oxidative stress

38:25 – how a low-carb diet affects thyroid hormone production and conversion, causing a hypothyroid state; high-carb diets vs. low-carb diets for thyroid health

47:46 – insulin resistance is associated with reduced thyroid hormone conversion, but this doesn’t mean you should avoid carbohydrates  

51:39 – how caloric restriction affects thyroid status

55:04 – the effects of fasting on thyroid status

56:42 – T3 has positive feedback on its own production and what this means for thyroid hormone replacement

1:00:01 – the effects of PUFA and endotoxin on thyroid hormone activity

1:04:30 – the effects of micronutrients, specifically iron, vitamin A, selenium, and iodine, on thyroid hormone production, conversion, and activity

1:16:30 – increased thyroid activity increases macronutrient and micronutrient needs, but also improves micronutrient retention in the long-term

1:19:15 – the effects of environmental toxins (pesticides, industrial chemicals, heavy metals, etc.) on thyroid hormone production, conversion, and activity

1:25:20 – the effect of sleep on thyroid hormone production and conversion