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Neurology Exam Prep Podcast
Episode 64 - Neurologic Complications of Systemic Cancer Therapies
Feb 1, 2024
Exploring neurological complications of systemic cancer therapies, including chemotherapy-induced neurotoxicity, immune checkpoint inhibitors, and CAR-T cell therapy. Discussion on monitoring and managing neurotoxicity post-treatment, immune reconstitution inflammatory syndrome, and challenges in treating complications.
37:25
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Quick takeaways
- Leptomeningeal metastases are increasing due to better cancer therapies, challenging diagnosis and treatment.
- Paraneoplastic syndromes require collaboration between neurology and oncology specialists for effective management.
Deep dives
Direct Complications of Cancer: Metastases to the Brain and Spinal Cord
Cancer metastasizing elsewhere in the body can affect the nervous system, leading to symptoms like seizures. Leptomeningeal metastases, where cancer spreads to the spinal fluid space, are becoming more common as patients live longer due to better therapies, posing challenges in diagnosis and treatment.
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