Neurologic Complications of Systemic Cancer Therapies

This chapter explores a range of neurologic complications associated with systemic cancer therapies, encompassing topics such as methotrexate toxicity, chemotherapy-related neurovascular side effects, 'chemo brain,' and the neurotoxic effects of radiation therapy on the brain. It also delves into radiation-induced neuropathies, neurologic complications of immune checkpoint inhibitors, and the potential severe neurologic side effects of chimeric antigen receptor T cell therapy. The emphasis is on early recognition, aggressive management, and the evolving understanding of administering steroids in cancer treatment protocols.