"Pediatric Vaccine for COVID-19 Part 2: Update on the Vaccine for 5-11-yrs, Boosters, and Omicron"

In part 2 of this World Shared Practice Forum podcast, Dr. Paul Offit, Professor of Pediatrics in the Division of Infectious Disease and the Director of the Vaccine Education Center at The Children's Hospital of Philadelphia, updates listeners on the latest data in the field of COVID vaccination. He summarizes results from Pfizer’s phase 3 vaccine trial involving 5- to 11-year olds, and discusses the considerations behind the recommendation of a third "booster" vaccine dose for all eligible age groups. He also explains what is known about COVID virus variants, including Omicron. Learning Objectives: After listening to this podcast, learners will be able to: -Describe the basic structure and results of the Pfizer COVID vaccine trial involving five- to eleven-year-old children -Discuss the potential benefits of a third "booster" dose of COVID vaccine for different patient populations -Describe the risks of myocarditis and other inflammatory syndromes associated with COVID infection, and possibly with COVID vaccines -Compare the clinical characteristics of the emerging Omicron variant to earlier variants of the SARS-CoV-2 virus Articles referenced: • Offit PA. You Bet Your Life: From Blood Transfusions to Mass Vaccination, the Long and Risky History of Medical Innovation. 1st ed. Basic Books; 2021. (00:50) • Walter EB, Talaat KR, Sabharwal C, et al. Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age [published online ahead of print, 2021 Nov 9]. N Engl J Med. 2021;NEJMoa2116298. doi:10.1056/NEJMoa2116298 (2:52) • Daniels CJ, Rajpal S, Greenshields JT, et al. Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection: Results From the Big Ten COVID-19 Cardiac Registry. JAMA Cardiol. 2021;6(9):1078-1087. doi:10.1001/jamacardio.2021.2065 (11:30) Intial publication: December 14, 2021 Citation: Offit PA, Daniel D, Burns JP. Pediatric Vaccine for COVID-19: Update on COVID-19 vaccine for 5-11 year olds, booster doses, and the Omicron variant. 12/2021. Online Podcast. OPENPediatrics. Offit PA, Daniel D, Burns JP. Pediatric Vaccine for COVID-19 Part 2: Update on the Vaccine for 5-11-yrs, Boosters, and Omicron. 12/2021. Online Podcast. OPENPediatrics. https://youtu.be/BcktvXuIsyI. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu