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Science Friday

FDA Panel Rejects MDMA Therapy For PTSD

Jul 22, 2024
FDA panel rejects MDMA therapy for PTSD despite its potential benefits. Methodology of clinical trials and concerns about data integrity were major factors in the decision. Guests, including a trial participant and a psychologist, shed light on the topic. The rejection raises questions about the future of psychedelic therapy in treating mental health conditions.
18:00

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Quick takeaways

  • FDA rejected MDMA therapy for PTSD due to concerns about clinical trial methodology.
  • Expert suggests alternative study designs for clearer insights into the effects of MDMA therapy.

Deep dives

Mixed Results from MDMA Therapy Clinical Trials

The FDA rejected MDMA therapy for PTSD after clinical trials by Lycos Therapeutics and MAPS, citing concerns about methodology. Trial participant Sarah Macnemy discussed her experience and highlighted the complex blend of psychotherapy and MDMA. Despite initial hope and hype, participants experienced both positive and negative outcomes, raising questions about the overall efficacy of the treatment.

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