Blood Bank Guy Essentials Podcast 019: Cryoprecipitate with Joe Chaffin
7 snips
Oct 19, 2016 
Joe Chaffin, a blood bank physician and educator behind the Blood Bank Guy resources. He unpacks five essentials of cryoprecipitate in short, clear segments. Topics include how cryo is made, what key proteins it contains, practical prep and shelf‑life rules, when to use it for fibrinogen replacement, and why its future may shrink as concentrates rise.
AI Snips
Chapters
Books
Transcript
Episode notes
Why Cryoprecipitate Needs Clarification
- Cryoprecipitate is the most misunderstood common blood product despite long use and evolving indications.
- Joe Chaffin frames five essentials to clarify production, contents, prep, use, and future of cryo.
Serendipitous Discovery At Stanford
- Cryo was discovered serendipitously when slow-thawing FFP left a gunky precipitate rich in factor VIII.
- Dr. Judith Poole and her team at Stanford first described making cryoprecipitate in 1964.
How Cryo Is Made Today
- In the U.S. cryo must start from whole blood–derived FFP frozen ≤−18°C within eight hours of collection.
- Slow thaw at 1–6°C and refrigerated centrifugation concentrate precipitate for refreezing as cryo.
