Stress-Free Longevity

Episode 11: Understanding Intermittent Fasting with Professor Michelle Harvie

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Jul 1, 2025
Professor Michelle Harvie, a clinical dietitian and researcher at the University of Manchester, dives into the fascinating world of intermittent fasting. She discusses how excess weight can harm internal organs, leading to serious health risks. With nearly three decades of research, she explains the metabolic flexibility gained from approaches like the 5:2 diet and time-restricted eating. Harvie also emphasizes the importance of understanding individual genetic factors that influence weight management and shares practical strategies for sustainable weight loss.
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INSIGHT

Excess Fat Harms Organs And Raises Disease Risk

  • Excess body fat accumulates inside organs and causes inflammation and disease risk.
  • Adult weight gain raises cancer and diabetes risk even with small yearly increases.
INSIGHT

BMI Is Useful But Limited

  • BMI is a useful proxy but has limits, especially across ethnic groups.
  • Waist-to-height ratio and central fat better predict diabetes and cardiovascular risk.
INSIGHT

Where Fat Lands Depends On Capacity And Genetics

  • Subcutaneous fat fills first, then ectopic fat builds in organs when storage capacity is exceeded.
  • Genetics, sex and ethnicity influence where people store fat and related disease risk.
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