Energized with Dr. Mariza

663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr

Jul 18, 2025
Dr. Scott Sherr, a visionary physician and expert in mitochondrial and nervous system healing, joins to unveil why many women feel both wired and tired. He dives into the crucial role of GABA, a calming neurotransmitter often depleted in midlife, leading to anxiety and insomnia. Delving into mitochondrial dysfunction, he offers practical, science-backed strategies to restore energy and joy naturally. The conversation emphasizes optimizing health through lifestyle changes, improving mental well-being, and reclaiming vitality at any age.
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INSIGHT

GABA and Mitochondria in Midlife

  • GABA is a calming neurotransmitter that declines during midlife, contributing to anxiety, insomnia, and mood issues.
  • Mitochondrial dysfunction also undermines energy, sleep, and joy, creating a cycle of stress and burnout.
ADVICE

Calm Nervous System for Sleep

  • Address middle-of-the-night awakenings and inability to return to sleep by calming the nervous system.
  • Use targeted interventions; sleep aids alone often do not resolve underlying nervous system overdrive.
ANECDOTE

Summer Juggle Anecdote

  • Scott Sherr juggle four kids and a clinical practice during summer camps.
  • Summer brings freedom for kids but creates challenges for parents to find uninterrupted work time.
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