
Plain English with Derek Thompson America Isn’t Ready for the Weight-Loss-Drug Revolution That’s Coming
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Jan 20, 2023 Susan Z. Yanovski, co-director of the Office of Obesity Research at NIH, discusses a groundbreaking shift in how America approaches weight loss. She highlights recent advancements in weight-loss medications like semaglutide, which could change the treatment landscape. The conversation challenges the belief that weight loss is solely about willpower, instead emphasizing biological factors. Yanovski also addresses the societal impact of these drugs, from health care implications to how they might reshape perceptions of diet and responsibility.
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Weight: Choice vs. Disease
- Weight has been viewed as a consequence of choices, not a disease.
- This view neglects biological and genetic factors influencing weight.
Body's Resistance to Weight Loss
- The body resists weight loss, making it hard to maintain.
- Hormonal changes triggered by dieting can increase hunger and slow metabolism.
Bariatric Surgery's Effectiveness
- Bariatric surgery alters hormones and the GI tract, leading to sustained weight loss.
- It's effective but invasive, prompting a search for less invasive alternatives.

