ResusX:Podcast Dual Defib Strategies
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Feb 11, 2025 
Dr. Tarlan Hedayati, an expert in cardiac arrest resuscitation, shares her profound knowledge on dual defibrillation strategies. She delves into the significance of dual sequential defibrillation in improving outcomes for shock-refractory VFib patients. Discover how vector change and timing can enhance the effectiveness of shocks. Dr. Hedayati also discusses findings from the DOSE-VF trial, shedding light on neurological survival rates. This enlightening conversation is essential for anyone involved in managing cardiac arrest scenarios.
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First Human Defibrillation
- In 1947, a 14-year-old undergoing heart surgery went into V-fib.
- The surgeon, aware of animal studies, successfully used internal electrodes to restore sinus rhythm, marking the first successful defibrillation in a human.
First DSED Case Series
- In 1994, the first case series on dual sequential external defibrillation (DSED) was published.
- Five patients in refractory V-fib were successfully resuscitated using this technique.
DOSE-VF Trial Results
- The DOSE-VF trial compared standard defibrillation, vector change, and DSED.
- DSED showed a trend towards improved outcomes, although the study was terminated early due to a paramedic shortage.