The Thomistic Institute

The Plasma Membrane: Boundary and Bridge at the Edge of Life – Prof. Keith Kozminski

Oct 14, 2025
Keith Kozminski, Associate Professor of Biology at the University of Virginia, dives deep into the fascinating world of the plasma membrane. He discusses its role as a boundary and bridge for cellular functions, touching on selective permeability and the structural importance of proteins and lipids. Kozminski explores advanced models of membrane dynamics, highlighting discoveries from super-resolution microscopy that challenge conventional views. His insights connect basic biology with synthetic methodologies, emphasizing the membrane's complexity and crucial functions in living systems.
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INSIGHT

Membrane Is Boundary And Interface

  • The plasma membrane is a specialized boundary that compartments, insulates, communicates, and selectively transports between inside and outside the cell.
  • Keith Kozminski emphasizes that membrane function derives from its structure of lipids and proteins.
INSIGHT

Protein Structures Impose Specificity

  • Proteins provide transport and communication functions while lipids establish compartmentalization and insulation in membranes.
  • Kozminski shows a potassium channel as a structural pipe that enforces ion specificity by shape.
ANECDOTE

Stained-Glass Ion Channel Story

  • Kozminski shares a whimsical example: a stained-glass window of an ion channel made by a retired researcher at Harvard.
  • He suggests such imagery could liven up Newman Center windows with scientific motifs like potassium channels.
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