Metabolic Mind GLP-1 and Ketosis: Novel Mental Health Treatments
Dec 26, 2023
World-renowned psychiatrist Dr. Roger McIntyre joins to discuss the potential of GLP1 medications like Wegovy and Ozempic in treating mental health disorders, comparing them to ketogenic therapy. They explore the intersection of medication effects and ketogenic therapy, the role of brain energy in psychiatric treatments, and the evolution and hope in psychiatric care.
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Brain Energy and Mental Illness
- Mental illnesses may be caused by abnormal brain cell energy utilization affecting their survival and function.
- GLP-1 system dysfunction could contribute, offering a new target to reset brain energy homeostasis for treatment and prevention.
GLP-1's Dual Brain Effects
- GLP-1 agonists improve mood indirectly via weight loss and diabetes control, and directly by affecting brain receptors in cognition and emotion regions.
- These drugs may reset brain circuits responsible for thinking, emotion, and pleasure, overlapping effects with lifestyle therapies.
GLP-1 as Brain Protectors
- GLP-1 medications act as brain protective agents by reducing inflammation and harmful proteins like amyloid.
- They boost brain resiliency and reduce risks linked to various mental illnesses across all ages.