Science Friday

How Agatha Christie Used Chemistry To Kill (In Books)

14 snips
Aug 18, 2025
Join Kathryn Harkup, a chemist-turned-author, as she unravels the deadly secrets behind Agatha Christie's use of poison in her mysteries. With a background in pharmacy, Harkup explains how Christie's chemistry knowledge enriched her storytelling. Discover the allure of toxicology, the dual nature of poisons, and the science behind crime-solving. Harkup also reflects on how societal perceptions of toxicity have shifted, shedding light on Christie's personal encounters with lethal plants that inspired her infamous plots.
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INSIGHT

Christie’s Scientific Imagination

  • Agatha Christie displayed wide imagination and scientific accuracy in her choice and use of poisons.
  • Her creativity extended to deployment, detection, and narrative signaling within plots.
ANECDOTE

Christie’s Pharmacy Training

  • Agatha Christie trained during WWI as a dispenser, hand-mixing prescriptions and working with hazardous compounds.
  • She learned both the technical and practical pharmacy skills that informed her novels' accuracy.
INSIGHT

Bacterial Poisons And Historical Timing

  • Christie understood bacterial agents as deliberate murder weapons before antibiotics were widespread.
  • She later avoided such plots after antibiotics reduced their lethality.
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