In the fifth episode of this six-part podcast series about the late career stage, physicist María Teresa Dova outlines how she is preparing colleagues years in advance to ensure a smooth handover of her lab at the University of La Plata, in Argentina.

But in the United States, when the principal investigator leaves it is likely the lab itself will close down, Gould discovers. For microbiologist Roberto Kolter, emeritus professor at Harvard Medical School in Boston, Massachusetts, this meant gradually downsizing his team before retirement, so all members had a clear timeframe in which to finish their work.

Often what happens to the contents of a lab is decided by the institution. Equipment such as freezers are often given to other research groups, while unique resources — such as Kolter’s 10,000 strong collection of bacterial strains created from his years of research — are kept and managed by the institution.

Chemist Craig Merlic, executive director of the University of California Center for Laboratory Safety in Los Angeles, stresses that it is important to think about the fate of hazardous lab materials to prevent future accidents.

Sometimes there isn’t time to plan, as experienced by immunologist Carol Shoshkes Reiss at New York University, when she had to suddenly close her lab due to a lack of funds. Shoshkes Reiss shares the surprising feeling she experienced after this abrupt closure — relief.

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