Oncotarget

Blood Filtration Stabilizes Advanced Pancreatic Cancer: A Case Report

Jul 24, 2025
Explore a groundbreaking case report on a unique treatment for advanced pancreatic cancer. A patient using extracorporeal blood filtration showed remarkable clinical improvements, experiencing reduced pain and no new tumor growth over a year. The innovative Seraph® 100 device targets circulating tumor cells, believed to spread cancer. This approach raises exciting possibilities but also highlights the need for more research to validate these early findings.
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ANECDOTE

Patient's Blood Filtration Journey

  • A 51-year-old woman with advanced pancreatic cancer chose blood filtration over chemotherapy.
  • After 9 to 12 treatments, her disease remained stable and she had less pain and opioid use.
INSIGHT

Blood Filtration's Potential Mechanism

  • Removing circulating tumor cells (CTCs) may limit cancer progression.
  • Filtration might reduce pro-inflammatory cytokines that influence pain.
INSIGHT

Novel Outcomes in Pain and Disease

  • Pain relief mechanism is unclear but may involve fewer tumor cells or inflammation.
  • This is the first case showing stable disease and symptom reduction with CTC filtration.
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